Function that assigns a logical (STATUS_LIKELY_GERMLINE_HETEROZYGOUS) reflecting whether a variant is likely heterozygous (germline) - based on allelic fraction (AF_TUMOR), presence in gnomAD and dbSNP, and no presence in TCGA and COSMIC

Function that assigns a logical (STATUS_LIKELY_GERMLINE_HETEROZYGOUS) reflecting whether a variant is likely heterozygous (germline) - based on allelic fraction (AF_TUMOR), presence in gnomAD and dbSNP, and no presence in TCGA and COSMIC

Usage

het_af_germline_status(sample_calls)

Arguments

sample_calls

data frame with sample variant calls