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Processes the purple.cnv.somatic.tsv file. and selects columns of interest.

Usage

purple_cnv_som_process(x)

Arguments

x

Path to purple.cnv.somatic.tsv file.

Value

List with two elements:

  • tab: Tibble with more condensed columns.

  • descr: Description of tibble columns.

Examples

x <- system.file("extdata/purple/purple.cnv.somatic.tsv", package = "gpgr")
(pp <- purple_cnv_som_process(x))
#> $tab
#> # A tibble: 59 × 9
#>    Chr       Start       End    CN `CN Min+Maj` `Start/End SegSupport` Method   
#>    <fct>     <int>     <int> <dbl> <chr>        <chr>                  <chr>    
#>  1 chr1          1 123605522   1   0+1          TELOMERE-CENTROMERE    BAF_WEIG…
#>  2 chr1  123605523 200044314   2   1+1          CENTROMERE-DUP         BAF_WEIG…
#>  3 chr1  200044315 200044570   2.8 1+1.8        DUP-DUP                STRUCTUR…
#>  4 chr1  200044571 248956422   2   1+1          DUP-TELOMERE           BAF_WEIG…
#>  5 chr2          1  93139350   2   1+1          TELOMERE-CENTROMERE    BAF_WEIG…
#>  6 chr2   93139351 219955359   2   1+1          CENTROMERE-BND         BAF_WEIG…
#>  7 chr2  219955360 225225069   1   0+1          BND-BND                BAF_WEIG…
#>  8 chr2  225225070 242193529   2   1+1          BND-TELOMERE           BAF_WEIG…
#>  9 chr3          1  92214015   1   0+1          TELOMERE-CENTROMERE    BAF_WEIG…
#> 10 chr3   92214016 198295559   2   1+1          CENTROMERE-TELOMERE    BAF_WEIG…
#> # ℹ 49 more rows
#> # ℹ 2 more variables: `BAF (count)` <chr>, `GC (windowCount)` <chr>
#> 
#> $descr
#> # A tibble: 7 × 2
#>   Column               Description                                              
#>   <chr>                <chr>                                                    
#> 1 Chr/Start/End        Coordinates of copy number segment                       
#> 2 CN                   Fitted absolute copy number of segment adjusted for puri…
#> 3 CN Min+Maj           CopyNumber of minor + major allele adjusted for purity   
#> 4 Start/End SegSupport Type of SV support for the CN breakpoint at start/end of…
#> 5 Method               Method used to determine the CN of the region. Allowed v…
#> 6 BAF (count)          Tumor BAF after adjusted for purity and ploidy (Count of…
#> 7 GC (windowCount)     Proportion of segment that is G or C (Count of COBALT wi…
#>